NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Biotechnology (IJBT) >
IJBT Vol.09 [2010] >
IJBT Vol.09(3) [July 2010] >


Title: Evolutionary interrelationships among polyomaviruses based on nucleotide and amino acid variations
Authors: Bhattacharjee, Soumen
Keywords: Large T-antigen (LTAg)
polyomavirus
viral protein 1 (VP1)
Issue Date: Jul-2010
Publisher: CSIR
Abstract: Polyomaviruses (PyVs), members of the family Polyomaviridae, are strictly vertebrate resident viruses implicated in various pathogenic conditions including neoplasias, especially in human. This study aims to review both nucleotide and amino acid sequences of large T-antigen (LTAg), virion protein 1 (VP1) gene and also whole genomes of all known PyVs till date, in ascertaining phylogenetic relationships among themselves. The study detected genomic recombinations within the oncoprotein LTAg coding sequences of PyV group, and identified unique nucleotide and amino acid positions in the conserved regions of PyV-LTAg coding sequence, which can facilitate strain differentiations in clinical samples.
Page(s): 252-264
ISSN: 0975-0967 (Online); 0972-5849 (Print)
Source:IJBT Vol.09(3) [July 2010]

Files in This Item:

File Description SizeFormat
IJBT 9(3) 252-264.pdf1.91 MBAdobe PDFView/Open
 Current Page Visits: 746 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 625093 since 06-Feb-2009  Last updated on 28-Nov-2014Webmaster: nopr@niscair.res.in