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Title: <i style="">In-vitro</i> testing of anti-HIV activity of some medicinal plants
Authors: A Rege, Anuya
Y Ambaye, Ramkrishna
A Deshmukh, Ranjana
Keywords: Anti-HIV
Medicinal plant
Mangrove plants
<i style="">Ocimum sanctum</i>
<i style="">Withania somnifera</i>
<i style="">Tinospora cordifolia</i>
<i style="">Avicennia officinalis</i>
<i style="">Rhizophora mucronata</i>
Issue Date: Jun-2010
Publisher: CSIR
Series/Report no.: <b style="">Int. cl.<sup>8</sup></b>—A61K 36/00, A61P 31/12, A61P 31/18.
Abstract: Medicinal plants namely <i style="">Ocimum sanctum </i>Linn.,<i style=""> Withania somnifera </i>Dunal, <i style="">Tinospora cordifolia </i>(Willd.) Miers. ex Hook.f. & Thoms., <i style="">Avicennia officinalis</i> Linn. and <i style="">Rhizophora mucronata </i>Lam. were screened for anti-HIV activity in the present study. <i style="">O</i>.<i style=""> sanctum</i>, <i style="">T. cordifolia</i>, <i style="">A. officinalis</i> and <i style="">R. mucronata</i> showed anti-HIV potential by inhibiting the virus by 2 different mechanisms. Interference with the gp120/CD4 interaction and inhibition of viral Reverse Transcriptase (RT) contributed to the overall anti-viral activity <i style="">in vitro</i>. Among these plants <i style="">A</i>.<i style=""> officinalis</i> and <i style="">R</i>.<i style=""> mucronata</i> are mangrove plants and their medicinal properties are rarely reported.
Description: 193-199
Appears in Collections:IJNPR Vol.1(2) [June 2010]

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