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IJTK Vol.09(3) [July 2010] >


Title: Evaluation of Ayurvedic compound formulations III- Laghugangadhar Churna
Authors: Rathi, Anshu
Rai, Vartika
Khatoon, Sayyada
Rastogi, Subha
Rawat, Ajay Kumar Singh
Mehrotra, Shanta
Pandey, M M
Keywords: Ayurvedic drugs
Standardization
Laghugangadhar Churna
HPTLC
Issue Date: Jul-2010
Publisher: CSIR
IPC CodeInt. Cl.8: A61K36/00, A61P1/04, A61P1/06, A61P1/10, A61P1/16
Abstract: Standardization of a compound Ayurvedic formulation is essential for establishing the authenticity, quality and efficacy of Ayurvedic medicines/finished herbal product. Laghugangadhar Churna is a compound formulation containing Cyperus rotundus (rhizome), Symplocos racemosa (stem bark), Woodfordia fruticosa (flower), Aegle marmelos (fruit pulp) and Holarrhena antidysenterica (seeds) as ingredients. It is one of the most effective and widely used remedy for diarrhoea and dysentery. To achieve the desired aim four samples of Laghugangadhar Churna were procured from different Ayurvedic pharmacies and were investigated by microscopy, physico-chemical parameters and high performance thin layer chromatography (HPTLC). The microscopic analysis of samples revealed starch grains in three ingredients viz. C. rotundus, S. racemosa and W. fruticosa. These plant species could be differentiated with the help of other diagnostic characters. HPTLC analysis of all four samples revealed the presence of all the ingredients in compound formulations as determined by simultaneous application of authentic ingredients. The diagnostic spots would be utilized as standardization profile. The physico-chemical data of the formulation assists in maintaining standard limits of Laghugangadhar Churna.
Page(s): 576-580
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Source:IJTK Vol.09(3) [July 2010]

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