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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.48 [2010] >
IJEB Vol.48(07) [July 2010] >
| Title: | Resistance to heavy metal toxicity in organisms under chronic exposure |
| Authors: | Bozhkov, Anatoliy
Vladimir Padalko, Vladimir
Dlubovskaya, Viktoria
Menzianova, Natalia |
| Keywords: | Heavy metal ions
Hormesis
Organism resistance |
| Issue Date: | Jul-2010 |
| Publisher: | CSIR |
| Abstract: | The rate of changes of heavy metal ions concentrations in the organism
or biological system will determine the choice of strategy of realization of
heavy metal ions effect and, consequently, the biological effect itself. Which
of the possible strategies will dominate, depend on the rate of changes of
concentration of heavy metal ions in biological systems, functional activity of
organism at the moment of metal action and on metals chemical properties.
Keeping this view, the present review deals with the concept of time-based
alterations of concentration of heavy metal ions (TACMI) in biological systems.
On the basis of TACMI concept formation of organism resistance to metal ions
action could be explained. In the event of slow increase of its concentration
in organism, it produces induction of metallothioneins, other stress-proteins
and relative changes in the whole metabolic system. This, first of all, results
in formation of new specific epigenotypes, which provide higher resistance
(hormesis effect) not only to metal ions that induced this effect, but also to
such stress-factors as high temperature (at least, for micro-algae cells). |
| Page(s): | 679-696 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.48(07) [July 2010]
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