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IJC-B Vol.49B [2010] >
IJC-B Vol.49B(06) [June 2010] >


Title: Zinc chloride-catalyzed one-pot synthesis of 3-[2-(3-methyl-4,5-dihydro-furo[2,3-c]­pyrazol-1-yl)thiazol-4-yl]-chromen-2-ones via a three component reaction
Authors: Kumar, P Vijaya
Reddy, K Manoher
Rao, V Rajeswar
Keywords: 2-Acetylbutyrolactone
thiazole
pyrazole
benzo¬pyran-2-one
4,5-dihydrofuropyrazole
one-pot synthesis
Issue Date: Jun-2010
Publisher: CSIR
Abstract: A simple and convenient procedure for the synthesis of 3-[2-(3-methyl-4,5-dihydro-furo[2,3-c]pyrazol-1-yl)-thiazol-4-yl]-chro­­men-2-ones 4a-f is described through anhydrous zinc chloride-catalyzed one pot condensation of 3-(2-bromoacetyl)­coumarin, thiosemicarbazide and 2-acetylbutyrolactone in good yields. The title compounds 4a-f are also synthesized via an alternative procedure.
Page(s): 836-839
Source:IJC-B Vol.49B(06) [June 2010]

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