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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(06) [June 2010] >
| Title: | Synthesis, antimicrobial and insecticidal activity of some new cinnoline based chalcones and cinnoline based pyrazoline derivatives |
| Authors: | Gautam, Nidhi
Chourasia, O P |
| Keywords: | Cinnoline
chalcone
pyrazoline
antibacterial activity
antifungal activity
insecticidal activity |
| Issue Date: | Jun-2010 |
| Publisher: | CSIR |
| Abstract: |
4-Methyl-3-acetyl
cinnoline used as a precursor to synthesize some new cinnoline based chalcones 3a-l. Reaction of chalcone with
hydrazine hydrate in acetic acid yields the cinnoline based pyrazoline
derivatives 4a-l. The structures of synthesized compounds have been confirmed by elemental analysis, IR and NMR spectral studies and evaluated for their
antibacterial activity against Bacillus subtilis, Escherichia coli, Staphylococcus aureaus and Klebsiella pneumoniae, antifungal activity against Aspergillus flavus, Fusarium oxysporum,
Aspergillus niger and Trichoderma viridae and insecticidal
activity against Periplaneta americana.
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| Page(s): | 830-835 |
| Source: | IJC-B Vol.49B(06) [June 2010]
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