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Title: Synthesis, antimicrobial and insecticidal activity of some new cinnoline based chalcones and cinnoline based pyrazoline derivatives
Authors: Gautam, Nidhi
Chourasia, O P
Keywords: Cinnoline
antibacterial activity
antifungal activity
insecticidal activity
Issue Date: Jun-2010
Publisher: CSIR
Abstract: <smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="country-region"><smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="place"><smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="City"> 4-Methyl-3-acetyl cinnoline used as a precursor to synthesize some new cinnoline based chalcones <b style="">3a-l</b>. Reaction of chalcone with hydrazine hydrate in acetic acid yields the cinnoline based pyrazoline derivatives <b style="">4a-l</b>. The structures of synthesized compounds have been confirmed by elemental analysis, IR and NMR spectral studies and  evaluated for their antibacterial activity against <i style="">Bacillus subtilis, Escherichia coli, Staphylococcus aureaus</i> and <i style="">Klebsiella pneumoniae</i>, antifungal activity against <i style="">Aspergillus flavus, Fusarium oxysporum, Aspergillus niger</i> and <i style="">Trichoderma viridae</i> and insecticidal activity against <i style="">Periplaneta americana.</i> </smarttagtype></smarttagtype></smarttagtype>
Description: 830-835
Appears in Collections:IJC-B Vol.49B(06) [June 2010]

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