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IJTK Vol.03(4) [October 2004] >

Title: Hepatoprotective effect of few Ayurvedic herbs in patients receiving antituberculus treatment
Authors: Sharma, Y K
Singh, Harbans
Mehra, B L
Keywords: Hepatitis
Hepatoprotective activity
Issue Date: Oct-2004
Publisher: CSIR
IPC CodeInt. Cl.7: A61K35/78, A61P31/06, A61P1/16
Abstract: Under the antituberculosis treatment (ATT) drug therapy, inclusion of a hepatoprotective drugs is not mandatory but in Indian scenario these are prescribed by most of the physicians. In present clinical trial three groups of patients receiving antituberculosis treatment have been studied to evaluate the hepatoprotective effect of few Ayurvedic herbs. The first group of 10 patients was given capsules Liv-600 containing hydroalcoholic extract of Daruharidra (Berberis aristata) roots, Kakmachi (Solanum nigrum) whole plant, Ghritakumari (Aloe vera) ariel parts. Second Group was given a standardized decoction of herb Bhumyamalaki (Phyllanthus fraternus). Third group was kept on ATT and a placebo starch capsule for equal duration. The trial was conducted for 12 weeks from initiation of ATT and liver functions were periodically evaluated to assess the hepatoprotective effect of drugs under trial. At the end of trial, Group first and second exhibited their hepatoprotective efficiency over the placebo.
Page(s): 391-396
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Source:IJTK Vol.03(4) [October 2004]

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