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Indian Journal of Traditional Knowledge (IJTK) >
IJTK Vol.03 [2004] >
IJTK Vol.03(3) [July 2004] >
| Title: | Investigation on the wound healing activity of Tilvadi ghrita : a herbal formulation |
| Authors: | Charde, M S
Hemke, A T
Fulzele, S V
Satturwar, P M
Kasture, A V
Dorle, A K |
| Keywords: | Tilvadi ghrita
Wound healing activity
Herbal formulation |
| Issue Date: | Jul-2004 |
| Publisher: | CSIR |
| IPC Code: | Int Cl.7:A61K 35/78, A61K 35/20, A61P 29/00, A61P 17/02, A61P 31/02 |
| Abstract: | Tilvadi
ghrita (TG) is a ghee-based herbal formulation
claimed to promote wound healing in traditional practices. However no systematic
studies are reported in modern scientific literature with regard to the
verification of the traditional medicinal claims of TG. The present study was
undertaken to investigate and rationalize the wound healing activity of TG in
experimental rats. Tilvadi ghrita
increased the tensile strength which is significantly improved over the untreated
wounds. Promotion of tensile strength demonstrates wound healing potential of
TG in incision wound which may probably be due to promotion of collagenation.
This data is further supported by observation of histopathological response in
healed tissues which reveal that TG promotes keratinization, epithelization,
collagenation and fibrosis. TG also demonstrates its healing potential in
excision wound model with significant reduction in wound contraction area with
faster healing. |
| Page(s): | 247-252 |
| ISSN: | 0975-1068 (Online); 0972-5938 (Print) |
| Source: | IJTK Vol.03(3) [July 2004]
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