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Title: Synthesis and antimicrobial activity of some 3-alkyl-4-(arylmethyleneamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones
Authors: Kahveci, Bahittin
Bekircan, Olcay
Karaoğlu, Şengül Alpay
Keywords: Antimicrobial activity;B. subtilis;Candida species;1,2,4-triazolone;triazolyl acetates;acetylhydrazines
Issue Date: Dec-2005
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D
Abstract: Eight new ethyl Nı-(3-methyl-4-arylmethyleneamino-4,5-di­hydro-1H-1,2,4-triazolyl-5-one)acetates 2 and Nı-(3-methyl-4-arylmethyleneamino-4,5-dihydro-1H-1,2,4-triazolyl-5-one)acetyl­hydrazines 3 have been synthesized. The structures of the compounds have been confirmed by IR and 1H NMR spectra and microanalysis. The compounds show some antimicrobial activities. Compound 2a shows antibacterial activity against B. subtilis. Compounds 3a, 3b and 3d have antifungal activity against Candida species.
Page(s): 2614-2617
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(12) December 2005]

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