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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(11) [November 2005] >
| Title: | Synthesis and antihypertensive activity of new 1,4-dihydropyridines |
| Authors: | Hadizadeh, Farzin
Hassanabad, Zahra Fatehi
Bamshad, Mohammad
Poorsoghat, Hamed
Hassanabad, Mohammad Fatehi |
| Keywords: | antihypertensive activity
1,4-dihydropyridines
imidazole
desoxycorticosterone acetate |
| Issue Date: | Nov-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D//A 61 P 9/12 |
| Abstract: | A series of
1,4-dihydropyridines bearing dimethylamino 2a-f or 1H-imidazol-1-yl
3a-f side chain in the 2 position have been synthesized from
unsubstituted ones 1a-f and tested for antihypertensive activity in desoxycorticosterone acetate (DOCA)-induced hypertensive rats. All the compounds have been found
to be less active than nifedipine. |
| Page(s): | 2343-2347 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(11) [November 2005]
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