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Title: Synthesis and antihypertensive activity of new 1,4-dihydropyridines
Authors: Hadizadeh, Farzin
Hassanabad, Zahra Fatehi
Bamshad, Mohammad
Poorsoghat, Hamed
Hassanabad, Mohammad Fatehi
Keywords: antihypertensive activity
desoxycorticosterone acetate
Issue Date: Nov-2005
Publisher: CSIR
Series/Report no.: <b>Int</b>.<b>Cl</b>.<b><sup>7</sup> C 07</b><b> D//A 61 P 9/12 </b>
Abstract: A series of 1,4-dihydropyridines bearing dimethylamino <b>2a-f</b> or 1<i>H</i>-imidazol-1-yl <b>3a-f</b> side chain in the 2 position have been synthesized from unsubstituted ones <b>1a-f</b> and tested for antihypertensive activity in desoxycorticosterone acetate (DOCA)-induced hypertensive rats. All the compounds have been found to be less active than nifedipine.
Description: 2343-2347
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(11) [November 2005]

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