Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/9221
Title: Regioselective one-pot synthesis of 3,5-diarylpyrazoles
Authors: Lokhande, P D
Waghamare, B Y
Sakate, S S
Keywords: Diarylpyrazolines
pyrazoles
chalcones
hydrazine hydrate
flavanones
flavones
pyrazolines
Issue Date: Nov-2005
Publisher: CSIR
Series/Report no.: <b> Int.Cl.<sup>7</sup> C 07 D</b>
Abstract: The 3,5-diarylpyrazolines and pyrazoles have been easily synthesized in excellent yields by the reaction of 2'-hydroxy┬şchalcones with hydrazine hydrate. The 2'-hydroxychalcones are converted into flavanones and flavones by simple cyclisation methods and then into pyrazolines and pyrazoles, respectively. Alternatively, one-pot synthesis of pyrazoles has also been achieved by converting 2'-hydroxychalcones into pyrazolines and thereafter their dehydrogenation using I<sub>2</sub>-DMSO reagent. The regiochemistry of pyrazoles obtained via pyrazolines and from flavones has been compared.
Description: 2338-2342
URI: http://hdl.handle.net/123456789/9221
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(11) [November 2005]

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