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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(11) [November 2005] >
| Title: | Regioselective one-pot synthesis of 3,5-diarylpyrazoles |
| Authors: | Lokhande, P D
Waghamare, B Y
Sakate, S S |
| Keywords: | Diarylpyrazolines
pyrazoles
chalcones
hydrazine hydrate
flavanones
flavones
pyrazolines |
| Issue Date: | Nov-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D |
| Abstract: | The 3,5-diarylpyrazolines and pyrazoles have
been easily synthesized in excellent yields by the reaction of 2'-hydroxychalcones
with hydrazine hydrate. The 2'-hydroxychalcones are converted into flavanones
and flavones by simple cyclisation methods and then into pyrazolines and
pyrazoles, respectively. Alternatively, one-pot synthesis of pyrazoles has also
been achieved by converting 2'-hydroxychalcones into pyrazolines and thereafter
their dehydrogenation using I2-DMSO reagent. The regiochemistry of
pyrazoles obtained via pyrazolines and from flavones has been compared. |
| Page(s): | 2338-2342 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(11) [November 2005]
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