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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(10) [October 2005] >
| Title: | Novel clay-catalysed expeditious cyclization to bis-benzothiazepine |
| Authors: | Singh, Pravin K
Srivastava, Vishal
Singh, J
Siddiqui, I R |
| Keywords: | Benzothiazepine
clay-catalyzed
Claisen-Schmidt condensation
microwave irradiation
fungicide |
| Issue Date: | Oct-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D // A 61 P 31/10 |
| Abstract: | A microwave-expediated,
high yielding synthesis of 4,4'-bis(2''-aryl-2'',3''-dihydro-1'',5''-benzothiazepin-4"-yl)bibenzyls 3a-j involving Claisen-Schmidt condensation of 4,4'-diacetylbibenzyl with aromatic aldehyde at room temperature
followed by cyclocondensation with 2-aminothiophenol on
montmorillonite K 10 clay in solvent-free condition under microwave is
reported.All compounds show promising antifungal activity against Fusarium oxysporum
and Penicillium
citrinum. Structure-activity relationships for the screened
compounds are discussed. |
| Page(s): | 2178-2182 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(10) [October 2005]
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