NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(10) [October 2005] >


Title: Synthesis and biological activity of some 3-imidazo[1,2-]pyridin-2-yl-chromen-2-one and 3-indolizin-2-yl-chromen-2-one
Authors: Kumar, P Vijaya
Rao, V Rajeswar
Keywords: Coumarins
aminopyridines
cyclization reaction
indolizines
antitubercular
antiviral
anticancer
Issue Date: Oct-2005
Publisher: CSIR
IPC CodeInt.Cl.7 C 07 D 209/04 // A 61 P 31/06, 31/12, 35/00
Abstract: Condensation of 3-(2-bromoacetyl)coumarins 1 with various 2-aminopyridines 2 in the solid state under solvent-free conditions yield 3-imidazo[1,2- ]pyridin-2-yl-chromen-2-ones 3. Condensation of 1 with 2-methylpyridines in dry benzene affords N-alkylpyridinium salts 5. These undergo cyclization reaction when heated with sodium bicarbonate to give indolizines 6. The structures of newly prepared compounds have been confirmed from analytical and spectral data. Some of the compounds exhibit antitubercular, antiviral and anticancer activities.
Page(s): 2120-2125
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.44B(10) [October 2005]

Files in This Item:

File Description SizeFormat
IJCB 44B(10) 2120-2125.pdf66.03 kBAdobe PDFView/Open
 Current Page Visits: 477 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 623179 since 06-Feb-2009  Last updated on 13-Nov-2014Webmaster: nopr@niscair.res.in