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Title: Synthesis, characterization and antibacterial activity studies on some fluorine containing quinoline-4-carboxylic acids and their derivatives
Authors: Holla, B Shivarama
Poojary, K Narayana
Poojary, Boja
Bhat, K Subrahmanya
Kumari, N Suchetha
Keywords: Quinoline-4-carboxylic acids
antibacterial activity
Issue Date: Oct-2005
Publisher: CSIR
Series/Report no.: <b>Int</b>.<b>Cl</b>.<b><sup>7</sup> C 07 D 215/00 // A 61 P 31/04</b>
Abstract: A series of 3-substituted-1,2,4-triazolo[3,4-<i style="">b</i>]-1,3,4-thiadiazol-6-yl-2-(2,4-dichloro-5-fluorophenyl)quinolines <b>5 </b>have been synthesized by the condensation of hitherto unreported quinoline-4-carboxylic acids <b>3</b> with various 3-substituted-4-amino-5-mercapto-1,2,4-triazoles <b>4</b>. The structures of newly synthesized compounds have been confirmed on the basis of elemental analysis, IR, <sup>1</sup>H NMR and mass spectral data. The newly synthesized compounds are evaluated for their antibacterial activities.
Description: 2114-2119
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(10) [October 2005]

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