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Title: Synthesis, characterization and antibacterial activity studies on some fluorine containing quinoline-4-carboxylic acids and their derivatives
Authors: Holla, B Shivarama
Poojary, K Narayana
Poojary, Boja
Bhat, K Subrahmanya
Kumari, N Suchetha
Keywords: Quinoline-4-carboxylic acids;Fluoroheterocycles;1,2,4-triazoles;1,3,4-thiadiazoles;antibacterial activity
Issue Date: Oct-2005
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D 215/00 // A 61 P 31/04
Abstract: A series of 3-substituted-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazol-6-yl-2-(2,4-dichloro-5-fluorophenyl)quinolines 5 have been synthesized by the condensation of hitherto unreported quinoline-4-carboxylic acids 3 with various 3-substituted-4-amino-5-mercapto-1,2,4-triazoles 4. The structures of newly synthesized compounds have been confirmed on the basis of elemental analysis, IR, 1H NMR and mass spectral data. The newly synthesized compounds are evaluated for their antibacterial activities.
Page(s): 2114-2119
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(10) [October 2005]

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