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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(10) [October 2005] >
| Title: | Synthesis, characterization and antibacterial activity studies on some fluorine containing quinoline-4-carboxylic acids and their derivatives |
| Authors: | Holla, B Shivarama
Poojary, K Narayana
Poojary, Boja
Bhat, K Subrahmanya
Kumari, N Suchetha |
| Keywords: | Quinoline-4-carboxylic acids
Fluoroheterocycles
1,2,4-triazoles
1,3,4-thiadiazoles
antibacterial activity |
| Issue Date: | Oct-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D 215/00 // A 61 P 31/04 |
| Abstract: | A series of
3-substituted-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazol-6-yl-2-(2,4-dichloro-5-fluorophenyl)quinolines
5 have been synthesized
by the condensation of hitherto unreported quinoline-4-carboxylic acids 3
with various 3-substituted-4-amino-5-mercapto-1,2,4-triazoles 4. The structures of newly synthesized
compounds have been confirmed on the basis of elemental analysis, IR, 1H
NMR and mass spectral data. The newly synthesized compounds are evaluated for
their antibacterial activities. |
| Page(s): | 2114-2119 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(10) [October 2005]
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