Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/9199
Title: Synthesis of 5<i>H</i>-dibenzo(<i>b,f</i>)azepine-5-carboxylic acid [3-chloro-2-(substitutedphenyl)-4-oxoazetidin-1-yl]amide from 5<i>H</i>-dibenzo(<i>b,f</i>) azepine-5-carbonyl chloride
Authors: Bhatt, Pralav V
Patel, Pravin M
Keywords: 5<i>H</i>-dibenzo(<i>b,f</i>)azepine-5-carbonyl chloride
5<i>H</i>-dibenzo(<i>b,f</i>)azepine-5-acid hydrazide
5<i>H</i>-dibenzo­(<i>b,f</i>)aze­pine-5-carboxylic acid (4-methoxybenzylidene)-hydrazide
5<i>H</i>-dibenzo(<i>b,f</i>)azepine-5-carboxylic acid [3-chloro-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]amide
Issue Date: Oct-2005
Publisher: CSIR
Series/Report no.: <b> Int.Cl.<sup>7</sup> C 07 D</b>
Abstract: 5<i>H</i>-Dibenzo(<i>b,f</i>)azepine-5-carbonyl chloride <b>1 </b>has been prepared from 5<i>H</i>-dibenzo(<i>b,f</i>)azepine by phosgenation, which has been then treated with hydrazine hydrate to give 5<i>H</i>-dibenzo(<i>b,f</i>)azepine-5-acid hydrazide <b>2</b>. It has been reacted with various aromatic aldehydes to afford 5<i>H</i>-dibenzo(<i>b,f</i>)azepine-5-carboxylic acid-(substitutedbenzylidene)hydrazide <b>3a-j</b>.<b> </b>The synthesis of 5<i>H</i>-dibenzo(<i>b,f</i>)azepine-5-carboxylic acid [3-chloro-2-(substitutedphenyl)-4-oxoazetidin-1-yl]amide <b>4a-j</b> has been achieved by the reaction of <b>3</b> with chloroacetyl chloride in presence of triethylamine. The products have been characterized by elemental analysis, IR,<sup> 1</sup>H NMR and mass spectral studies.
Description: 2082-2086
URI: http://hdl.handle.net/123456789/9199
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(10) [October 2005]

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