NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(10) [October 2005] >

Title: Synthesis and antineoplastic activity of some 16- benzylidene substituted steroidal oximes
Authors: Dubey, Sonal
Jindal, Dharam Paul
Piplani, Poonam
Keywords: benzylidine substituted steroidal oximes
antineoplastic activity
anticancer assay
Issue Date: Oct-2005
Publisher: CSIR
IPC CodeInt.Cl.7 C 07 J // A 61 P
Abstract:  Novel 16-benzylidine substituted steroidal oximes in the androstene series have been designed, synthesized and evaluated for in vitro antineoplastic activity at NCI, Bethesda, USA against 3-cell lines using one dose primary anticancer assay. Of the compounds tested, 3β-hydroxy derivatives 24 (DPJ-1059), 26 (DPJ-1081), 28 (DPJ-870), 30 (DPJ-818), 32 (DPJ-854) and 3β-acetoxy derivatives 25 (DPJ-1061), 27 (DPJ-1083), 31 (DPJ-817) and 33(DPJ-900) have been found to be quite active.
Page(s): 2126-2137
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.44B(10) [October 2005]

Files in This Item:

File Description SizeFormat
IJCB 44B(10) 2126-2137.pdf175.99 kBAdobe PDFView/Open
 Current Page Visits: 569 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 170983 since 01-Sep-2015  Last updated on 30-Jun-2016Webmaster: