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Title: Phase transfer catalyzed synthesis under ultrasonic irradiation and bioactivity of N '-(4, 6-disubstituted-pyrimidin-2-yl)- N-(5-aryl-2-furoyl)thiourea derivatives
Authors: Ke, Shao-Yong
Wei, Tai-Bao
Xue, Si-Jia
Duan, Li-Ping
Li, Jing-Zhi
Keywords: Bioactivity;thiourea derivatives;phase transfer catalyst;dicotyledon plant;Amaranthus retroflexus L
Issue Date: Sep-2005
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D
Abstract: Ten new N'-(4, 6-disubstituted-pyrimidin-2-yl)-N-(5-aryl-2-furoyl)thioureas have been synthesized using PEG-400 as solid-liquid phase transfer catalyst under ultrasonic irradiation. Their structures were exactly confirmed by IR, 1H NMR and elemental analysis. The preliminary biological tests show that compound 7b has better inhibitory activities against root and stalk of dicotyledon plant (such as Amaranthus retroflexus L.) in higher concentration.
Page(s): 1957-1960
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(09) [September 2005]

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