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Title: N -Fmoc-Peptide azides: Synthesis, isolation, characterization and utility in the extension of peptide chains
Authors: Babu, Vommina V Suresh
Vasanthakumar, Ganga-Ramu
Patil, Basanagoud S
Keywords: Fmoc-peptide acid;peptide acid azide;Fmoc-peptide isocyanate
Issue Date: Sep-2005
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 K
Abstract: Syntheses of N-Fmoc-peptide azides employing acid chloride as well as mixed anhydride methods have been carried out. The resulting Fmoc-peptide azides prepared have been isolated as solids in good yield (75-92 %) and are found to be analytically pure. Further, long shelf life of N-Fmoc-peptide azides makes them useful in the extension of peptide chains.
Page(s): 1853-1858
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(09) [September 2005]

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