Please use this identifier to cite or link to this item:
Title: Synthesis and characterisation of isoquinolinyl quinazolines and a study of their antiviral and antifungal activities
Authors: Pandey, V K
Pathak, L P
Mishra, S K
Keywords: Isoquinolinyl quinazolines;Antiviral activity;antifungal activity
Issue Date: Sep-2005
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D 215/00 //A 61 P 31/10, 31/12
Abstract: Anthranilic acid on treatment with an aromatic acid chloride in pyridine gives 2-aryl-4-oxo-3H-benzoxazines 1 which reacts with p-aminobenzoic acid to afford 2-aryl-3-p-carboxylatophenyl-4-oxo-3H-quinazolines 2. Interaction of 2 with benzoin in the presence of polyphosphoric acid results 2-aryl-3-(3',-4'-diphenyl­isocoumarinyl)-4-oxo-3H-quinazolines 3, which on reaction with 2-amino-5-aralkyl-1,3,4-thiadiazoles yield 2-aryl-3-[5'-aralkyl-1',3',4'-thiadiazolyl-{2'-(3'',4''-diphenyl-1"-oxo-isoquino­linyl)}]-4-oxo-3H-quinazolines 4. The antifungal and antiviral activities of 4 have been reported.
Page(s): 1940-1943
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(09) [September 2005]

Files in This Item:
File Description SizeFormat 
IJCB 44B(9) 1940-1943.pdf52.05 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.