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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(08) [August 2005] >
| Title: | Synthesis, X-ray diffraction study and biological activity of 7-hydroxy-4-methylquinolin-2(1H)-one |
| Authors: | Deshmukh, M B
Desai, Savita Dhongade
Chavan, S S |
| Keywords: | methylquinoline
microwave-assisted method
X-ray diffractometry
orthorhombic
antibacterial activity
antifungal activity |
| Issue Date: | Aug-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D 215/00 // A 61 P 31/10, 31/04 |
| Abstract: | The compound
7-hydroxy-4-methylquinolin-2(1H)-one (HMQ) has been synthesized by an
easy and efficient microwave-assisted method.The structure of the compound has
been confirmed on the basis of its IR, 1HÂ NMR spectral data and
elemental analyses. The sample has been subjected to X-ray diffractometry to
elucidate structural information. The structure of the compound has been found
to be orthorhombic belonging to base centered system. The accountability of
strain broadening effects with respect to natural particle size is also
examined and discussed. The compound has been screened for the antibacterial
and antifungal activities. |
| Page(s): | 1659-1662 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(08) [August 2005]
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