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Title: Synthesis of 1,3,4-oxadiazoles carrying imidazole moiety
Authors: Frank, Priya V
Kalluraya, Balakrishna
Keywords: 1,3,4-Oxadiazoline;hydrazones;antibacterial activity;antifungal activity
Issue Date: Jul-2005
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D 233/00, 27/10 // A 61 P 31/04, 31/10
Abstract: A new series of 1,3,4-oxadiazoline derivatives 5a-l have been obtained by cyclisation of various hydrazones 4 with acetic anhydride. The hydrazones 4 in turn are obtained by the reaction of appropriate carbonyl compound with 2-methyl-5-nitroimidazole-1-acethydrazide 3. The new products are characterized by spectral and analytical data. Most of the tested compounds show promising antibacterial and antifungal activity.
Page(s): 1456-1459
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(07) [July 2005]

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