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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(07) [July 2005] >
| Title: | Synthesis of 1,3,4-oxadiazoles carrying imidazole moiety |
| Authors: | Frank, Priya V
Kalluraya, Balakrishna |
| Keywords: | 1,3,4-Oxadiazoline
hydrazones
antibacterial activity
antifungal activity |
| Issue Date: | Jul-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D 233/00, 27/10 // A 61 P 31/04, 31/10 |
| Abstract: | A new series of 1,3,4-oxadiazoline
derivatives 5a-l have been obtained
by cyclisation of various hydrazones 4
with acetic anhydride. The hydrazones 4
in turn are obtained by the reaction of appropriate carbonyl compound with
2-methyl-5-nitroimidazole-1-acethydrazide 3.
The new products are characterized by spectral and analytical data. Most of the
tested compounds show promising antibacterial and antifungal activity. |
| Page(s): | 1456-1459 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(07) [July 2005]
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