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|Title:||Synthesis of 1,3,4-oxadiazoles carrying imidazole moiety|
|Authors:||Frank, Priya V|
|Keywords:||1,3,4-Oxadiazoline;hydrazones;antibacterial activity;antifungal activity|
|IPC Code:||Int.Cl.7 C 07 D 233/00, 27/10 // A 61 P 31/04, 31/10|
|Abstract:||A new series of 1,3,4-oxadiazoline derivatives 5a-l have been obtained by cyclisation of various hydrazones 4 with acetic anhydride. The hydrazones 4 in turn are obtained by the reaction of appropriate carbonyl compound with 2-methyl-5-nitroimidazole-1-acethydrazide 3. The new products are characterized by spectral and analytical data. Most of the tested compounds show promising antibacterial and antifungal activity.|
|Appears in Collections:||IJC-B Vol.44B(07) [July 2005]|
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