Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/9115
Title: Synthesis of 3<i style="">H</i>, 9<i style="">H</i>, 10<i style="">H</i>, 10a<i style="">H</i>-10-aryl-2-aryliminothiazolidino[4,5-<i style="">b</i>][1,5]benzodiazepines and their alkoxyphthalimide derivatives
Authors: Singh, Bhawani
Baregama, Lalit K
Ahmed, Maqbool
Dixit, Neha
Talesara, G L
Issue Date: Jun-2005
Publisher: CSIR
Series/Report no.: <b>Int</b>.<b>Cl</b>.<b><sup>7</sup> C 07 D</b>
Abstract: Synthesis and characterization of 3<i style="">H</i>, 9<i style="">H</i>, 10<i style="">H</i>, 10a<i style="">H</i>-10-aryl-2-aryliminothiazolidino[4,5-<i style="">b</i>][1,5]benzodiazepines and their alkoxyphthalimide derivatives are described. Cyclization of 5-arylidene-2-aryliminothiazolidin-4-ones <b style="">1a-i </b>with <i style="">o</i>-phenylenediamine in xylene furnishes the corresponding 1,5-benzodiazepines <b style="">2a-i</b>.<b style=""> </b>In another reaction route, <b style="">1a-i </b>when condensed with ω-bromoalkoxyphthalimides <b style="">3a-c</b> give 3-alkoxyphthalimido-5-arylidene-2-aryliminothiazolidin-4-ones <b style="">4a-a'</b> which on cyclization with <i style="">o</i>-phenylenediamine produce 9<i style="">H</i>, 10<i style="">H</i>, 10a<i style="">H</i>-3-N-(<i>n</i>-alkoxyphthalimido)-10-aryl-2-aryliminothiazolidino[4,5-<i style="">b</i>][1,5]benzodiazepines <b style="">5a-a' </b>in good yields.
Description: 1243-1247
URI: http://hdl.handle.net/123456789/9115
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(06) [June 2005]

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