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|Title:||A novel and short convergent approach for N-aryl-5-aminomethyl-2-oxazolidinone derivatives Linezolid and DUP-721|
Reddy, G Om
Dubey, P K
|IPC Code:||Int.Cl.7 C 07 D|
|Abstract:||A new convergent and short approach for oxazolidinone class of antibacterial agents, Linezolid and DUP-721, has been achieved by condensing 3-chloro-2-((phenoxycarbonyl)oxy) propyl azide with aryl amine followed by reductive acetylation. This one pot approach for N-aryl-5-azidomethyl- 2-oxazolidinone could provide access for rapid preparation of various oxazolidinone analogues.|
|Appears in Collections:||IJC-B Vol.44B(06) [June 2005]|
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