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IJC-B Vol.44B [2005] >
IJC-B Vol.44B(05) [May 2005] >


Title: Synthesis of novel 2,' 3'-unsaturated nucleoside
Authors: Singh, Virendra
Issue Date: May-2005
Publisher: CSIR
IPC Code Int.Cl.7 C 07 H
Abstract: 5'-tert-Butyldimethylsilyl-5-iodo-6-methyluridine 1 is con¬≠verted to the bisxanthate 2 by reaction with carbon disulphide, followed by alkylation. The bisxanthate 2 on reduction with tri-n-butyltin hydride and desilylation affords the unsaturated nucleo¬≠side, 2',3'-didehydro-2',3'-dideoxy-5-iodo-6-methyluridine 4.
Page(s): 1095-1097
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.44B(05) [May 2005]

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