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Title: Synthesis of novel 2,' 3'-unsaturated nucleoside
Authors: Singh, Virendra
Issue Date: May-2005
Publisher: CSIR
Series/Report no.: <b> Int</b>.<b>Cl</b>.<b><sup>7</sup> C 07 H</b>
Abstract: 5'-<i>tert</i>-Butyldimethylsilyl-5-iodo-6-methyluridine <b>1 </b>is con­verted to the bisxanthate <b>2</b> by reaction with carbon disulphide, followed by alkylation. The bisxanthate <b>2</b> on reduction with tri-<i>n</i>-butyltin hydride and desilylation affords the unsaturated nucleo­side, 2',3'-didehydro-2',3'-dideoxy-5-iodo-6-methyluridine <b>4</b>.
Description: 1095-1097
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(05) [May 2005]

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