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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(05) [May 2005] >
| Title: | Synthesis of novel 2,' 3'-unsaturated nucleoside |
| Authors: | Singh, Virendra |
| Issue Date: | May-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 H |
| Abstract: | 5'-tert-Butyldimethylsilyl-5-iodo-6-methyluridine
1 is converted to the bisxanthate 2 by reaction with carbon
disulphide, followed by alkylation. The bisxanthate 2 on reduction with
tri-n-butyltin hydride and desilylation affords the unsaturated nucleoside,
2',3'-didehydro-2',3'-dideoxy-5-iodo-6-methyluridine 4. |
| Page(s): | 1095-1097 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(05) [May 2005]
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