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Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.48 [2010] >
IJEB Vol.48(06) [June 2010] >
| Title: | Wound healing potential of ethanolic extract of Kalanchoe pinnata Lam. leaf—A preliminary study |
| Authors: | Nayak, B Shivananda
Marshall, Julien R
Isitor, Godwin |
| Keywords: | Excision wound
Hydroxyproline
Kalanchoe pinnata |
| Issue Date: | Jun-2010 |
| Publisher: | CSIR |
| Abstract: | The extract of K. pinnata was evaluated for its wound healing activity by using excision wound model in rats. On
day 11, animals treated with the ethanolic leaf extract exhibited 86.33 %
reduction in the wound area, compared to petroleum jelly treated control
(69.36%) and the mupirocin treated standard (85.49%). The hydroxyproline content
of extract treated animals was higher, as compared to control and the standard
groups. Histological analysis was also consistent with the proposal that K. pinnata leaf extract exhibits
significant wound healing potential. The increased rate of wound contraction
and hydroxyproline content in the extract treated animals supports the claims
made by traditional healers of the benefits obtained from the medicinal use of K. pinnata. |
| Page(s): | 572-576 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.48(06) [June 2010]
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