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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.48 [2010] >
IJEB Vol.48(06) [June 2010] >
| Title: | Evaluation of genotoxic effects in male Wistar rats following microwave exposure |
| Authors: | Kumar, Sanjay
Kesari, Kavindra Kumar
Behari, Jitendra |
| Keywords: | Catalase
Glutathione peroxidase
Micronuclei
Microwave radiation
Reactive oxygen species
Superoxide dismutase |
| Issue Date: | Jun-2010 |
| Publisher: | CSIR |
| Abstract: | Wistar rats (70 days
old) were exposed for 2 h a day for 45 days continuously at 10 GHz [power
density 0.214 mW/cm2, specific absorption rate (SAR) 0.014 W/kg] and 50 GHz (power density 0.86 μW/cm2,
SAR 8.0 ×10-4 W/kg). Micronuclei (MN), reactive oxygen species
(ROS), and antioxidant enzymes activity were estimated in the blood cells and
serum. These radiations induce micronuclei formation and significant increase
in ROS production. Significant changes in the level of serum glutathione
peroxidase, superoxide dismutase and catalase were observed in exposed group as
compared with control group. It is concluded that microwave exposure can be
affective at genetic level. This may be an indication of tumor promotion, which
comes through the overproduction of reactive oxygen species. |
| Page(s): | 586-592 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.48(06) [June 2010]
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