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dc.contributor.authorKamila, M M-
dc.contributor.authorMondal, N-
dc.contributor.authorGhosh, L K-
dc.description.abstractA simple, sensitive and accurate UV spectrophotometric method has been developed for the determination of eprosartan mesylate in raw material and experimental tablets. Beer’s law was obeyed in the concentration range 2-30 μg mL⁻¹ for the drug (λ = 232 nm) with an apparent molar absorptivity and Sandell sensitivity of 2.8 × 10⁴ L.mol⁻¹cm⁻¹ and 0. 01854 µg cm⁻²/0.001A, respectively. The limits of detection and quantitation were calculated to be 0.3623 and 1.098 µg mL⁻¹, respectively. Results were validated statistically according to ICH guidelines. Validation of the method yielded good results in the concerning range (2-30 µg mL⁻¹), linearity (r² = 0.9998), precision and accuracy. The excipients present in the experimental tablets did not interfere with the method.en_US
dc.sourceIJCT Vol.15(2) [March 2008]en_US
dc.subjectEprosartan mesylateen_US
dc.subjectUV spectrophotometryen_US
dc.titleSpectrophotometric determination of eprosartan mesylate in raw material and experimental tabletsen_US
Appears in Collections:IJCT Vol.15(2) [March 2008]

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