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|Title:||Synthesis and pharmacological evaluation of heterocycles from benzocycloheptenones|
Vasireddy, Nageswara Rao
|Series/Report no.:||<b>Int</b>.<b>Cl</b>.<b><sup>7</sup> C 07 C 13/24</b>|
|Abstract:||A new series of benzocyclohepten-5-one thiosemicarbazones <b style="">2a,b</b> obtained by condensation of benzocyclohepten-5-ones <b style="">1a,b</b> with thiosemicarbazide, are treated with monochloroacetic acid, 3-bromopropionic acid, chloroacetyl chloride, 1,3-dichloroacetone, phenacyl bromide and acetic anhydride, respectively to yield nitrogen and sulphur containing heterocycles. The structures of all these compounds have been determined by analytical and spectral methods. A few of them exhibit promising antibacterial activity.|
|Appears in Collections:||IJC-B Vol.44B(04) [April 2005]|
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