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Title: Synthesis and pharmacological evaluation of heterocycles from benzocycloheptenones
Authors: Venkateswarlu, Peesapati
Vasireddy, Nageswara Rao
Issue Date: Apr-2005
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 C 13/24
Abstract: A new series of benzocyclohepten-5-one thiosemicarbazones 2a,b obtained by condensation of benzocyclohepten-5-ones 1a,b with thiosemicarbazide, are treated with monochloroacetic acid, 3-bromopropionic acid, chloroacetyl chloride, 1,3-dichloroacetone, phenacyl bromide and acetic anhydride, respectively to yield nitrogen and sulphur containing heterocycles. The structures of all these compounds have been determined by analytical and spectral methods. A few of them exhibit promising antibacterial activity.
Page(s): 783-788
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(04) [April 2005]

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