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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(03) [March 2005] >
| Title: | Synthesis, characterization and evaluation of antimicrobial activity of Mannich bases of some 2-[(4-carbethoxymethylthiazol-2-yl)imino]-4-thiazolidinones |
| Authors: | Altıntaş, Handan
Ateş, Öznur
Kocabalkanli, Ayşe
Birteksöz, Seher
Ötük, Gülten |
| Issue Date: | Mar-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D // A 61 P 31/04, 31/10 |
| Abstract: | A series of 5-(N,N-disubstituted aminomethyl)-2-[(4-carbethoxymethylthiazol-2-yl)imino]-4-thiazolidinones 4a-m
have been synthesized. Their structures are confirmed by elemental analyses and
spectral data (IR, 1H NMR, EIMS). The antibacterial activities
of the compounds against Staphylococcus
aureus ATCC 6538, Staphylococcus
epidermidis ATCC 12228, Escherichia
coli ATCC 8739, Klebsiella pneumoniae
ATCC 4352, Pseudomonas aeruginosa
ATCC 1539, Salmonella typhi, Shigella
flexneri, Proteus mirabilis ATCC 14153
and antifungal activity against Candida
albicans ATCC 10231 are tested using disk diffusion method. Some of the
compounds are found to have significant activity against
S. aureus ATCC 6538. |
| Page(s): | 585-590 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(03) [March 2005]
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