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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(03) [March 2005] >
| Title: | Stereoselective synthesis of (2R, 3S, 22R, 23E)-6, 6-ethylenedioxy-22-hydroxy- 2, 3- isopropylidenedioxy-24-methyl-5 -cholest-23-ene: An intermediate for the synthesis of castasterone, dolichosterone and brassinolide |
| Authors: | Hazra, Braja G
Kumar, Tirunahari Pavan
Pore, Vandana S |
| Issue Date: | Mar-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 J 5/00, 9/00 |
| Abstract: | Wittig reaction on (2R, 3S)-2,3-isopropylidenedioxy-6,6-ethylene-dioxy-5 -pregnane-(20S)-20-carbaldehyde 6,
furnishes stereoselcctively an 22(E)- , -unsaturated ketone 7, which on reaction with methyllithium
followed by 1,3-carbonyl transposition and stereoselective reduction with
DIBAL-H affords the title compound 10,
an intermediate for castasterone, dolichosterone and brassinolide. |
| Page(s): | 611-614 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(03) [March 2005]
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