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Title: New 1,3-dipolar cycloadducts of 3-azidoacetylcoumarins with DMAD and their antimicrobial activity
Authors: Kusanur, Raviraj A
Kulkarni, Manohar V
Issue Date: Mar-2005
Publisher: CSIR
IPC Code: Int.Cl.7 C 07 D 311/00 // A 61 P 31/04, 31/10
Abstract: 3-Bromoacetylcoumarins 1 have been treated with sodium azide in aqueous acetone to give 3-azidoacetylcoumarins 2 which on further reaction with dimethylacetylenedicarboxylate 3 in dry xylene produce 1,3-dipolar cycloadducts 4. All the newly synthesized azidoacetylcoumarins and their DMAD cycloadducts have been characterized by IR, NMR and mass spectroscopic techniques and also screened for their antimicrobial activity.
Page(s): 591-594
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.44B(03) [March 2005]

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