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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.44B [2005] >
IJC-B Vol.44B(01) [January 2005] >
| Title: | Reduction of aldehydes and oximes to their corresponding alcohols and amines by catalytic hydrogenation method |
| Authors: | Basappa
Doreswamy, B H
Mahendra, M
Mantelingu, K
Sridhar, M A
Prasad, J Shashidhara
Rangappa, K S |
| Issue Date: | Jan-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D 233/54 |
| Abstract: | The reduction of aldehydes such as
2-butyl-5-chloro-3H-imidazole-5-carbaldehyde
and veratraldehyde, which are pharmaceutical key intermediates, have been
reduced to alcohols by catalytic hydrogenation method in the presence of
magnesium and also oximes are reduced to primary amines successively by
magnesium/ammonium formate system, is a large scale feasible and cheaper
method. The crystal structure of the product, (2-butyl-5-chloro-3H-imidazole-4-yl)-methanol 1 is reported. |
| Page(s): | 148-151 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.44B(01) [January 2005]
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