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Indian Journal of Pure & Applied Physics (IJPAP) >
IJPAP Vol.43 [2005] >
IJPAP Vol.43(09) [September 2005] >
| Title: | Crystal growth and dissolution of brushite crystals by different concentration of citric acid solutions |
| Authors: | Parekh, Bharat B Joshi, M J |
| Keywords: | Crystal growth Brushite crystals Citric acid Calcium stones |
| Issue Date: | Sep-2005 |
| Publisher: | CSIR |
| IPC Code: | B01D9/100 |
| Abstract: | Calcium hydrogen phosphate dihydrate (CHPD) or brushite
crystals are well-known urinary crystals and frequently found in urinary
stones. The CHPD crystals were grown by the single diffusion gel growth
technique in sodium meta-silicate gel. The grown crystals were having platelet
and star shape morphologies. The maximum growth was observed for the first five
days, thereafter, the growth became almost steady. After achieving maximum
growth of CHPD crystals, the aqueous solutions having different molar
concentrations of citric acid were added into the supernatant solution
containing calcium chloride. In the case of low concentrations of citric acid,
the inhibition of the growth of CHPD crystals was observed, whereas for the
higher concentrations of citric acid the dissolution of the grown crystals was
observed. This indicates that the citric acid inhibits the growth of CHPD
crystals in the lower concentrations and dissolves them in the higher
concentrations. This supports the citrate inhibition theory of urinary calculi
and crystals. |
| Page(s): | 675-678 |
| ISSN: | 0975-1041 (Online); 0019-5596 (Print) |
| Source: | IJPAP Vol.43(09) [September 2005]
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