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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(05) [May 2010] >
| Title: | A facile synthesis of carvedilol, β-adrenergic blocking agent, via a key 5-substituted-2-oxazolidinone intermediate |
| Authors: | Madhusudhan, G
Kumar, B Anand
Chintamani, U S
Rao, M Narasimha
Udaykiran, D
Suresh, T
Kumar, V Kiran
Mukkanti, K |
| Keywords: | Carvedilol
5-substituted-2-oxazolidinone
impurity B
β-adrenergic blocking agent
β-amino alcohol |
| Issue Date: | May-2010 |
| Publisher: | CSIR |
| Abstract: | A
facile synthesis of Carvedilol via a
key 5-substituted-2-oxazolidinone intermediate is described and this approach
avoids the formation of bis side product (impurity B). This approach could be useful for the preparation of many
β-amino alcohols without formation of bis impurity. |
| Page(s): | 606-610 |
| Source: | IJC-B Vol.49B(05) [May 2010]
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