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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(05) [May 2010] >
| Title: | Studies on phosphine free Pd-salen complexes as effective catalysts for aqueous Suzuki reaction |
| Authors: | Borhade, Sanjay R
Waghmode, Suresh B |
| Keywords: | Suzuki reaction
biaryls
Pd-salen
phosphine-free
aryl boronic acid |
| Issue Date: | May-2010 |
| Publisher: | CSIR |
| Abstract: |
Palladium complexes of the salen ligands, N,N'-bis(salicylidene)-ethylenediamine
and N,N'-bis(salicylidene)-1,2-phenylenediamine have been explored for
their catalytic activity in a phosphine-free
aqueous Suzuki reaction. The various reaction parameters have been
systematically optimized with respect to various solvents, bases, temperatures
and Pd concentrations. The studies conclude that 1:1 DMF to water solvent
ratio, Na2CO3 as base and 0.5 mol% of palladium at 90°C is apt for Suzuki
reactions. Rapid transformation of substituted aryl iodides and aryl bromides
into corresponding biaryls has been observed with excellent yield ranging from
70-86%, under optimized conditions.
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| Page(s): | 565-572 |
| Source: | IJC-B Vol.49B(05) [May 2010]
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