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Research Journals >
Indian Journal of Chemical Technology (IJCT) >
IJCT Vol.12 [2005] >
IJCT Vol.12(3) [May 2005] >
| Title: | Adsorption equilibrium of 7-aminodeacetoxy cephalosporanic acid–cephalexin mixture onto activated carbon and polymeric resins |
| Authors: | Dutta, N N
Saikia, Monali Dutta |
| Keywords: | Cephalosporinic acid
adsorption isotherm
activated carbon
polymeric resin |
| Issue Date: | May-2005 |
| Publisher: | CSIR |
| IPC Code: | B01D15/08 |
| Abstract: | The adsorption of 7-aminodeacetoxy
cephalosporanic acid (7-ADCA) – cephalexin binary mixture in aqueous solution
has been studied using polymeric resins of two different types as well as
activated carbon. The adsorption intensity was found to be strongly dependent
on the aqueous phase pH and this dependence could be interpreted from a model
for neutral species adsorption in all cases. Single-solute isotherms for 7-ADCA
and cephalexin were correlated with the Langmuir, Freundlich and
Redlich-Peterson isotherm models, the Langmuir model being found to provide the
best fit of the experimental data. The differences in adsorption affinities of
the solute obtained for different adsorbents were interpreted from sorbent
surface chemistry and morphological structure. Experimental binary-solute
adsorption isotherms were compared with four different types of binary-solute Langmuir
models using single-solute parameters. The results showed that the difference
in saturation capacities affected the adsorption equilibrium. Furthermore,
three types of binary-solute Langmuir models were converted into the kinetic
form and one of them was used to calculate the association rate constants of
7-ADCA and cephalexin from experimental data. The adsorption rate curves for
7-ADCA and cephalexin appear to be typical of the first order kinetics. |
| Page(s): | 296-303 |
| ISSN: | 0975-0991 (Online); 0971-457X (Print) |
| Source: | IJCT Vol.12(3) [May 2005]
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