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IJEB Vol.48(05) [May 2010] >


Title: Free radicals: Their beneficial and detrimental effects on sperm function
Authors: Kothari, Shiva
Thompson, Aaron
Agarwal, Ashok
Plessis, Stefan S du
Keywords: Apoptosis
Acrosome reaction
Capacitation
DNA damage
Free radical
Sperm function
Issue Date: May-2010
Publisher: CSIR
Abstract: Free radicals are molecules with one or more unpaired electron(s) commonly found in seminal plasma. Physiologically, free radicals control sperm maturation, capacitation and hyperactivation, the acrosome reaction, and sperm-oocyte fusion. Pathologically, free radicals induce lipid peroxidation, DNA damage and apoptosis of spermatozoa. The present review deals with both the beneficial and detrimental effects of free radicals on sperm function.
Page(s): 425-435
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.48(05) [May 2010]

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