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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.48 [2010] >
IJEB Vol.48(05) [May 2010] >
| Title: | Free radicals: Their beneficial and detrimental effects on sperm function |
| Authors: | Kothari, Shiva
Thompson, Aaron
Agarwal, Ashok
Plessis, Stefan S du |
| Keywords: | Apoptosis
Acrosome reaction
Capacitation
DNA damage
Free radical
Sperm function |
| Issue Date: | May-2010 |
| Publisher: | CSIR |
| Abstract: | Free radicals are molecules with one or more
unpaired electron(s) commonly found in seminal plasma. Physiologically, free
radicals control sperm maturation, capacitation and hyperactivation, the
acrosome reaction, and sperm-oocyte fusion. Pathologically, free radicals
induce lipid peroxidation, DNA damage and apoptosis of spermatozoa. The present
review deals with both the beneficial and detrimental effects of free radicals
on sperm function. |
| Page(s): | 425-435 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.48(05) [May 2010]
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