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NPR Vol.4(5) [September-October 2005] >


Title: Therapeutics
Issue Date: Oct-2005
Publisher: CSIR
Abstract: Aegle marmelos Corr. (Hindi — Bael) leaves are used for several diseases in Ayurvedic and Unani system of medicine hence to evaluate analgesic, antipyretic and anti-inflammatory activities experimental studies were done by the scientists of University of Madras, Chennai, India and National Institute of Animal Health, Science City, Japan. The extracts of the leaves showed significant inhibition of the carrageenan-induced paw oedema and cotton-pellet granuloma in rats. The extracts also produced marked analgesic activity by reduction in the early and late phases of paw licking in mice. A significant reduction in hyperpyrexia in rats was also produced by the most of the extracts. In addition, all the extracts derived from the leaves showed antipyretic activity in mice made hyperthermic by dried yeast injection. The response of chloroform, diethyl ether and methanol extracts was almost comparable to that of Paracetamol. Thus, this study has confirmed the traditional claims [Veerappan Arul, Shigeru Miyazaki and Renganathan Dhananjayan, Studies on the anti-inflammatory, antipyretic and analgesic properties of the leaves of Aegle marmelos Corr., J Ethnopharmacol, 2005, 96(1-2), 159-163].
Page(s): 431-434
ISSN: 0975-1092 (Online); 0972-592X (Print)
Source:NPR Vol.4(5) [September-October 2005]

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