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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.46B [2007] >
IJC-B Vol.46B(12) December 2007] >
| Title: | A simple two-step synthesis of avenanthramides, constituents of oats (Avena sativa L) |
| Authors: | Kamat, Shrivallabh P
Parab, Sulaksha J |
| Keywords: | Oats
Avena sativa
Antioxidants
Avenanthramides
Anthranilic acid
Meldrum’s acid
2-[(carboxyacetyl)amino]benzoic acid |
| Issue Date: | Dec-2007 |
| Publisher: | CSIR |
| Abstract: | A simple two-step general procedure has been developed to prepare naturally occurring and synthetic avenanthramides, constituents of oats (Avena sativa L). Reaction of anthranilic acid 1 with Meldrum’s acid 2 gives half amide of malonic acid 3 which on condensation with different benzaldehyde derivatives 4a-m gives avenanthramides 5a-m of which 5a-d are natural, 5e-g are their methyl ethers and 5h-m are synthetic. |
| Page(s): | 2074-2078 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.46B(12) December 2007]
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