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IJC-B Vol.46B(12) December 2007] >


Title: Efficient synthesis of 6-aryl-12H-pyrido[2',3':4,5] pyrimido [1,2-a][1,8] naphthyridin-12-ones under microwave irradiation
Authors: Mogilaiah, K
Anitha, E
Vidya, K
Reddy, N Vasudeva
Keywords: 3-Aryl-2-chloro-1,8-napthyridines
2-aminonicotinic acid
-[2',3':4,5]pyrimido[1,2,-⍺][1,8]naphthyridin-12-ones
Microwave irradiation
Issue Date: Dec-2007
Publisher: CSIR
Abstract: A straightforward and highly efficient procedure has been described for the synthesis of 6-aryl-12H-pyrido[2',3':4,5]pyrimido [1,2-⍺][1,8]naphthyridin-12-ones 3 by the reaction of 3-aryl-2-chloro-1,8-naphthyridines 1 with 2-aminonicotinic acid 2 in glacial acetic acid under microwave irradiation. The products are obtained in very good yields and in a state of high purity. The structural assignments of compounds 3 were based on their elemental analyses and spectral (IR and ¹H NMR) data.
Page(s): 2071-2073
ISSN: 0376-4699
Source:IJC-B Vol.46B(12) December 2007]

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