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Title: Protective role of flavonoids in cardiovascular diseases
Authors: Nandave, Mukesh
Ojha, S K
Arya, D S
Keywords: Flavonoids;Cardioprotection;Cardiovascular diseases
Issue Date: Jun-2005
Publisher: CSIR
IPC Code: A61P 9/00, C07D 311/00
Abstract: Flavonoids are low molecular weight, polyphenolic compounds present in all vascular plants. They are primarily recognized as the pigments responsible for autumnal burst of hues and yellow, orange and red shades in flowers and fruits. Flavonoids have been shown to possess a variety of biological activities at nontoxic concentrations in living organisms. Compelling data from various in vivo and in vitro experimental and several epidemiological studies have demonstrated the beneficial effects of dietary flavonoids. The mechanisms of their cardioprotective effect have been thought to stem from their free radical scavenging, antioxidant, anti-thrombotic, anti-apoptotic and anti-hypertensive effects. Based on the results of clinical studies, it would be suffice to say that flavonoids could be promising cardio-protective agents
Page(s): 166-176
ISSN: 0975-1092 (Online); 0972-592X (Print)
Appears in Collections:NPR Vol.4(3) [May-June 2005]

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