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|Abstract:||A team of scientists at Department of Pharmacology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Tamaho-cho, Nakakoma-gun, Yamanashi, Japan has made a beverage from wine vinegar and grape juice (Budo-no-megumi™) for people who wish to obtain effective amount of both polyphenols and vinegar for their health. In this study, authors assessed its cardiovascular effects using an <i>in vivo</i> pentobarbital-anesthetized rat. A recommended dose of the beverage (3 ml/kg, p.o.) decreased the heart rate and mean blood pressure, while no significant change was detected in the electrocardiogram parameters (n = 6). These results suggest that the new beverage may be useful for people who are worried about palpitation and/or hypertension. More work will be required to estimate which components in the beverage are essential to the current results in addition to establishing its long-term efficacy [Sugiyama <i>et al</i>, <i>Nutr Res,</i><b> </b>2003,<b> 23</b>(9), 1291-1296].|
|ISSN:||0975-1092 (Online); 0972-592X (Print)|
|Appears in Collections:||NPR Vol.4(2) [March-April 2005]|
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