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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
NPR Vol.5 [2006] >
NPR Vol.5(1) [January-February 2006] >
| Title: | Development of quality control methods for polyherbal formulation, Chyawanprash |
| Authors: | Kasar, Rahul P
Laddha, K S
Chaudhary, Jayesh
Shukla, Anil |
| Keywords: | Chyawanprash
Phytoconstituents
Physicochemical Parameter
Standardization
Stability study |
| Issue Date: | Feb-2006 |
| Publisher: | CSIR |
| IPC Code: | Int. cl.7—A61K 35/78 |
| Abstract: | Chyawanprash is a
traditional polyherbal formulation which is widely, used as tonic, rejuvenator,
anabolic, immunomodulator and memory enhancer. Chyawanprash contains the pulp of Emblica officinalis Gaertn. as the
prime ingredient, along with powder and extract of several other herbs. It is
observed that the consistency and taste varies from one manufacturer to another.
Even these variations are observed in the same pharmaceutical company in
different manufacturing batches. Hence, it is the need of the hour to
standardize the raw materials to obtain product consistency. With the advent of
new analytical tools and sophisticated instrumental technology, the quality
assurance profile for a crude drug or its bioactive constituents can be made
possible. Two in-house batch of
Chyawanprash was prepared according to the procedure described in text Charaksamhita and remaining one
Chyawanprash sample was procured from market. These batches were evaluated by
physicochemical methods and its bio-efficacy was determined by various
biological methods like antioxidant study, microbial contamination study and
finally stability study was performed on the formulation according to the ICH
guidelines.
The results
of two in-house batches were
found in close proximation with the marketed batch. The method used for
determination of quality control of Chyanwanprash was found to be precise and
reproducible and can be used for quality control of other marketed formulations.
These studies on Chyawanprash were noticed reproducible and precise and may be
considered as the methods for its quality control. |
| Page(s): | 33-41 |
| ISSN: | 0975-1092 (Online); 0972-592X (Print) |
| Source: | NPR Vol.5(1) [January-February 2006]
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