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Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] >
NPR Vol.5 [2006] >
NPR Vol.5(2) [March-April 2006] >
| Title: | A review on antidepressant plants |
| Authors: | Dhingra, Dinesh Sharma, Amandeep |
| Keywords: | Depression Medicinal plants Antidepressants Herbal medicine |
| Issue Date: | Apr-2006 |
| Publisher: | CSIR |
| IPC Code: | Int. cl.7 — A61K 35/78, A61P 25/24 |
| Abstract: | Depression is a heterogeneous mood disorder that has been
classified and treated in a variety of ways. Although a number of synthetic
drugs are being used as standard treatment for clinically depressed patients,
they have adverse effects that can compromise the therapeutic treatment. Thus,
it is worthwhile to look for antidepressants from plants with proven advantage and favourable benefit-to-risk
ratio. A number of medicinal plants per se and medicines derived from
these plants have shown antidepressant properties by virtue of their medicinal
constituents. The causes of depression are decreased brain levels of monoamines
like noradrenaline, dopamine and serotonin. Therefore, drugs restoring the
reduced levels of these monoamines in the brain either by inhibiting monoamine
oxidase or by inhibiting reuptake of these neurotransmitters might be fruitful
in the treatment of depression. The present review is focused on the medicinal
plants and plant-based formulations having antidepressant activity in animal
studies and in humans. |
| Page(s): | 144-152 |
| ISSN: | 0975-1092 (Online); 0972-592X (Print) |
| Source: | NPR Vol.5(2) [March-April 2006]
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