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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
NPR Vol.5 [2006] >
NPR Vol.5(4) [July-August 2006] >
| Title: | Antitussive effect of Cuminum cyminum Linn. in guinea pigs |
| Authors: | Boskabady, Mohammad Hossin
Kiani, Sahar
Azizi, Hoda
Khatami, Tahereh |
| Keywords: | Cuminum cyminum
Cumin
Antitussive
Citric acid
Codeine |
| Issue Date: | Aug-2006 |
| Publisher: | CSIR |
| IPC Code: | Int. cl.7 — A 61 K 35/78, A61P 11/14 |
| Abstract: | Several
therapeutic effects including the effect on asthma and dyspnoea have been
described for the seeds of cumin, Cuminum cyminum Linn. In the present
study the antitussive effect of this plant was evaluated. The antitussive
effects of aerosols of two different concentrations of aqueous and macerated
extracts, Codeine and saline were testedÂ
on guinea pigs by counting the number of coughs produced due to aerosol
of citric acid 10 minutes after exposing animal to aerosols of different
solutions (n=5 for each solution). The results showed significant reduction of
cough number in the presence of both concentrations of aqueous and macerated
extracts and Codeine (P<0.01 to P<0.001). The cough number observed
in the presence of higher concentrations of aqueous and macerated extracts were
not significantly different than those of lower concentrations. In addition,
there was no significant difference between cough numbers observed in the
presence of both concentrations of extracts with that of Codeine. These results
indicated an antitussive effect of cumin which was comparable to that of
Codeine. |
| Page(s): | 266-269 |
| ISSN: | 0975-1092 (Online); 0972-592X (Print) |
| Source: | NPR Vol.5(4) [July-August 2006]
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