Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/7935
Title: Synthesis and study of chlorosubstituted 4-aroyl and 4-alkoyl-pyrazolines, pyrazoles and their effect on some flowering plants
Authors: Mahale, Jaishree D
Manoja, S C
Belsare, N G
Rajput, P R
Keywords: Valeric acid;chromanone;chromone;pyrazoline;pyrazole
Issue Date: Apr-2010
Publisher: CSIR
Abstract: Some new chlorosubstituted 4-aroyl/alkoylpyrazolines 5a,b and 4-aroyl/alkoylpyrazoles 7a,b have been synthesized by condensation of 1-(2′-hydroxy-3′-5′-dichlorophenyl)-3-aryl/alkyl-1-3-propanedione 3a,b and valeraldehyde by Baker-Venkatraman transformation of corresponding aroyl/alkoyloxyacetophenones. Aroyl/Alkoyloxyacetophenones 2a,b undergo intramolecular Claisen condensation to form 1-(2′-hydroxy-3′-5′-dichloro­phenyl)-3-aryl/alkyl-1,3-propanediones 3a,b which on treatment with aliphatic aldehyde in ethanol containing little piperidine forms 3-aroyl/alkoylchromanones 4a,b. From these 3-aroyl/alkoylchromanones 4a,b 4-aroyl/alkoylpyrazolines 5a,b are synthesized. 3-Aroyl/Alkoylchromanones 4a,b are converted into 3-aroyl/alkoylchromones 6a,b. The 3-aroyl/alkoylchromones 6a,b on treatment with Ph.NHNH2.HCl in dioxane containing small amount of piperidine furnish 4-aroyl/alkoylpyrazoles 7a,b. The structures of the newly synthesized chlorosubstituted 4-aroyl /alkoylpyrazolines 5a,b and 4-aroyl/alkoylpyrazoles 7a,b have been elucidated on the basis of spectral analysis and their homogeneity has been established by TLC.
Page(s): 505-511
URI: http://hdl.handle.net/123456789/7935
Appears in Collections:IJC-B Vol.49B(04) [April 2010]

Files in This Item:
File Description SizeFormat 
IJCB 49B(4) 505-511.pdf174.32 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.