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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(04) [April 2010] >
| Title: | Efficient synthesis of 9-aryl-6-(2-fluorophenyl)-1,2,4-triazolo[4,3- ] [1,8]naphthyridines using chloramine-T under microwave irradiation |
| Authors: | Mogilaiah, K
Dhanaja, K
Srivani, N
Chandra, A Vinay |
| Keywords: | 1,2,4-Triazole,1,8-naphthyridine
chloramine-T
micro¬wave irradiation |
| Issue Date: | Apr-2010 |
| Publisher: | CSIR |
| Abstract: | A simple and highly
efficient procedure has been described for the synthesis of 9-aryl-6-(2-fluorophenyl)-1,2,4-triazolo[4,3-
][1,8]naphthyridines 8 by
oxidation of the corresponding aryl aldehyde 3-(2-fluorophenyl)-1,8-naphthyridin-2-ylhydrazones
7 with chloramines-T in ethanol
under microwave irradiation. The products are obtained in good yields and in
state of high purity. The structures of the compounds 3-8 have been
established on the basis of spectral (IR, 1H NMR and MS) and
analytical data. |
| Page(s): | 500-504 |
| Source: | IJC-B Vol.49B(04) [April 2010]
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