NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(04) [April 2010] >

Title: A novel one pot room temperature ionic liquid mediated synthesis of 1,5-benzodiazepine ribofuranosides
Authors: Yadav, Ashok K
Kumar, Manoj
Yadav, Tripti
Jain, Renuka
Keywords: Benzodiazepines
ionic liquid
Issue Date: Apr-2010
Publisher: CSIR
Abstract: A novel one pot ecofriendly synthesis of 7-substituted/7,8-disubstituted-2,2,4-trisubstituted-1-(2′,3′,5′-tri-O-benzoyl-β-D-ribofuranosyl)-2,3-dihydro-1,5-benzodiazepines have been accomplished stepwise, i.e. reacting o-phenylenediamine and a ketone in the first step followed by addition of β-D-ribofuranose-1-bromo-2,3,5-tribenzoate. The ionic liquids employed are 1,3-di-n-butylimidazolium bromide [BBIM]Br, 1-butyl-3-methylimidazolium bromide [BMIM]Br, 1-butyl-3-methylimidazolium tetrafluoroborate, [BMIM]BF4, 1-butyl-3-methylimidazolium hexafluorophosphate [BMIM]PF6, and 1-methoxyethyl-3-methylimidazolium mesylate [MOEMIM]Ms. The yields (72-90%) of the targeted compounds are excellent.
Page(s): 461-468
Source:IJC-B Vol.49B(04) [April 2010]

Files in This Item:

File Description SizeFormat
IJCB 49B(4) 461-468.pdf.pdf133.56 kBAdobe PDFView/Open
 Current Page Visits: 985 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 168057 since 01-Sep-2015  Last updated on 29-Jun-2016Webmaster: