|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
NPR Vol.6 [2007] >
NPR Vol.6(5) [September-October 2007] >
| Title: | Evaluation of the antipyretic potential of methanol extract of the leaves of Abies spectabilis (D. Don) Spach. |
| Authors: | Visnoi, Satya Prakash
Basu, Anindya
Alam, S k Mahasin
Samanta, Soma
Jha, Tarun |
| Keywords: | Abies spectabilis
Antipyretic
Methanol extract
Yeast-induced pyrexia |
| Issue Date: | Oct-2007 |
| Publisher: | CSIR |
| IPC Code: | Int. cl.8— A61K 36/00, A61K 36/15, A61K 127/00, A61P 29/00 |
| Abstract: | Methanol extract of leaves of Abies
spectabilis (D. Don) Spach.
(MEAS) was evaluated for the antipyretic potential on normal body
temperature and yeast induced pyrexia in rats. MEAS showed significant activity
at intraperitonial (i.p.)
doses of 200 and 400mg/kg body weight. The extract, when administered at a dose
of 200mg/kg body weight caused significant lowering of body temperature up to
3h. With 400 mg/kg body weight dose it caused significant lowering of body
temperature up to 6h after administration. In the model of yeast induced
elevation of body temperature MEAS showed dose-dependant lowering of the body
temperature up to 4h at both the doses. The results obtained, were comparable to
that of paracetamol, a standard antipyretic agent. |
| Page(s): | 369-371 |
| ISSN: | 0975-1092 (Online); 0972-592X (Print) |
| Source: | NPR Vol.6(5) [September-October 2007]
|
|
