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Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
NPR Vol.6 [2007] >
NPR Vol.6(2) [March-April 2007] >
| Title: | Free radical scavenging activity of Lagenaria siceraria (Mol.) Standl. fruit |
| Authors: | Deshpande, J R
Mishra, M R
Meghre, V S
Wadodkar, S G
Dorle, A K |
| Keywords: | Lagenaria siceraria
Bottle gourd
Free radical scavenging activity
Cardiovascular diseases |
| Issue Date: | Apr-2007 |
| Publisher: | CSIR |
| IPC Code: | Int. cl.8— A61K 36/42, A61P 9/00, A61P 39/06 |
| Abstract: | Lagenaria siceraria (Mol.) Standl.
commonly known as Bottle gourd has been widely used as vegetable in India
especially by cardiac patients. Since this property may be correlated with the
presence of radical scavenging activity, extracts of the fruit were evaluated
for this purpose.The fruit was collected and epicarp, mesocarp and pulp
containing seeds were separated. Each of them was extracted with different
solvents in increasing order of polarity. Extracts were prepared using the
Soxhlet apparatus by serial extraction technique and their respective extractive
values were determined. All the extracts were assessed by 1,
1-Diphenyl-2-picrylhydrazyl (DPPH) assay. The maximum antioxidant activity was
observed in the acetone extract of fruit epicarp. Chemical investigation
revealed that radical scavenging activity may be due to the presence of
ellagitannins present in the acetone extract of epicarp. |
| Page(s): | 127-130 |
| ISSN: | 0975-1092 (Online); 0972-592X (Print) |
| Source: | NPR Vol.6(2) [March-April 2007]
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